Association study of variants in genes FTO, SLC6A4, DRD2, BDNF and GHRL with Binge Eating Disorder (BED) in Portuguese women

Date

2019-03

Embargo

Advisor

Coadvisor

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier
Language
English

Research Projects

Organizational Units

Journal Issue

Alternative Title

Abstract

A population based case-control study was conducted in Portuguese women with overweight/obesity to investigate the possible association of variants in genes FTO, SLC6A4, DRD2, BDNF and GHRL with binge eating disorder (BED). The distribution of seven polymorphisms was evaluated in 31 BED patients and 62 controls. No significant associations were found between polymorphisms and BED. Of interest, a markedly lower frequency of the FTO rs9939609 obesity risk A-allele was found in BED patients (0.290) in relation to the control group (0.402). Contrasting with anorexia nervosa and bulimia nervosa, our data suggest that rs9939609 A-allele has no potential role in BED.

Keywords

BED genetic susceptibility, FTO rs9939609 polymorphism, Obesity

Document Type

Journal article

Publisher Version

DOI: 10.1016/j.psychres.2019.01.047

Dataset

Citation

Palmeira, L., Cunha, M., Padez, C., Alvarez, M., Pinto-Gouveia, J., & Manco, L. (2019). Association study of variants in genes FTO, SLC6A4, DRD2, BDNF and GHRL with binge eating disorder (BED) in Portuguese women. Psychiatry Research, 273, 309-311. Doi: 10.1016/j.psychres.2019.01.047. Disponível no Repositório UPT, http://hdl.handle.net/11328/3506

TID

Designation

Access Type

Open Access

Sponsorship

Description