A transcritical bifurcation in an immune response model

The consequences of regulatory T cell (Treg) inhibition of interleukine 2 secretion are examined by mathematical modelling. We find a transcritical bifurcation that might explain two alternative scenarios: in one case the appearance of autoimmune responses and in another the suppression of the immune response.

Palavras-chave

Transcritical bifurcation, ODE model, Immunology, T cells, Tregs, Antigenic stimuli

Tipo de Documento

Artigo

Versão

VoR - Versão final publicada do editor

Versão da Editora

https://doi.org/10.1080/10236190903095291

Dataset

https://www.tandfonline.com/doi/full/10.1080/10236190903095291

Citação

Burroughs, N. J., Ferreira, M., Oliveira, B. M. P. M., & Pinto, A. A. (2011). A transcritical bifurcation in an immune response model. Journal of Difference Equations and Applications, 17(7), 1101-1106. https://doi.org/10.1080/10236190903095291. Repositório Institucional UPT. https://hdl.handle.net/11328/6332

Identificadores

https://hdl.handle.net/11328/6332
1023-6198
1563-5120

Tipo de Acesso

Acesso Restrito

Licença

Atribuição (CC-BY)

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